Volume 29, Issue 5, 2020
DOI: 10.24205/03276716.2020.1168
Therapeutic Effect of Acupuncture Combined with Duhuo Jisheng Decoction on Knee Osteoarthritis and Its Degree of Pain and Inflammatory Factors
Abstract
OBJECTIVE: To treat patients with knee osteoarthritis (KOA) with acupuncture combined with Duhuo Jisheng Decoction, and to analyze the effect of the combined method on KOA patients and the effect on pain level and inflammatory factors. METHODS: Ninety-five patients with KOA admitted to our hospital from August 2016 to September 2018 were selected as the main subjects and were clinically diagnosed.Patients were divided into a combination group (n=47, using Duhuo parasitic soup + acupuncture) and a control group (n=48, conventional western medicine) according to the random number table method; joint pain degree, swelling index and inflammatory response factor before and after treatment The level of change was recorded, and the total effective rate and adverse reactions of the two groups were recorded.RESULTS: The total effective rate was 93.62% in the combined group and 75.00% in the control group. The difference was statistically significant (P<0.05). After treatment, the pain level, swelling index and inflammatory factor level were significantly lower in the two groups. Before treatment, the difference was statistically significant (P<0.01); and the joint group had a pain degree of (2.31±0.26) points and a swelling index of (0.29±0.07), which were significantly lower than the control group [(5.24±0.38) points. (0.67±0.13)], the difference was statistically significant (P<0.01); the combined group TNF-α was (4.28±1.07) pg/mL, IL-1 was (167.65±42.84) pg/mL, (2.06± 0.62) ng/L and IL-1β were (1.46±0.39) mg/L, which were significantly lower than the control group [(8.05±1.86) pg/mL, (234.81±63.41) ng/L, (3.52±1.07) ng. /L, (3.18±1.03) mg/L], the difference was statistically significant (P<0.01); the incidence of adverse reactions in the combined group was 4.26%, which was significantly lower than that in the control group (21.28%). The difference was statistically significant (P<0.05).Conclusion: Duhuo Jisheng Decoction combined with acupuncture can significantly improve the degree of joint pain in KOA patients, effectively reduce the level of inflammatory factors and improve the therapeutic effect. It has important guiding significance for clinical treatment of KOA.
Keywords
acupuncture; arthritis; knee bone; Duhuo parasitic soup; pain degree; inflammatory factor