Volume 29, Issue 5, 2020
DOI: 10.24205/03276716.2020.1178
The association of preexisting cardiovascular risk and the disease severity of COVID-19: A meta-analysis
Abstract
Background: The exponential growth of novel 2019 Coronavirus disease (COVID-19) has set off a worldwide crisis. Although, its cause mild to moderate illness in major of patients; however, some peoples get critically ill. Peoples with underlying diseases, including cardiovascular complications, diabetics etc. are more susceptible to sever illness. Therefore, it is crucial to understand the association of these severe diseases and COVID-19 is crucial.
Design: This is a meta-analysis of observational studies assessing cardiovascular (CV) complications and the impact of CV comorbidities or risk variables (RF) of hospital-based COVID-19 patients mortality.
Methods: Data sources: PubMed, Scopus, and ISI from 1 December 2019 to 11 June 2020; References of qualified investigations; Abstract of the logical meetings; Cardiology sites. We have chosen to contemplate that report clinical results of patients with COVID-19 in the medical clinic. The principal result was death. Auxiliary results were CV side effects and CV functions observed during the COVID-19-related clinic. The separated information was recorded in Excel worksheets and investigated utilizing measurable programming (MedCalc, Open Meta-analyst R). We used a 95% CI level as a brief measure.
Results: As a result of 17 studies, 11% of the 54565 patients hospitalized had CV complications or CV related RF. Clinical and vascular complications were noted in 16.91% of cases during the observational period. In a meta-relapse study, cardiovascular disease (CVD) or RF was mainly associated with CVD in COVID-19 patients (p = 0.020). The occurrence of previous CVD or RF (p <0.001), mature age (p <0.001), and the advancement of cardiovascular intricacies when hospitalized (p = 0.040) was statistically significant.
Conclusions: CVD are elementary in COVID-19 patients, and alongside previous CV comorbidities and RF can prompt unfavorable clinical functions and mortality. Physician far and wide ought to know about this relationship to recognize patients at higher risk.
Keywords
association of preexisting , cardiovascular risk, disease severity of COVID-19