Volume 29, Issue 4, 2020


DOI: 10.24205/03276716.2020.882

Effects of Physical Activity on Quality of Life of Coronary Artery Bypass Grafted Patients: Re-Examining the Evidence from Randomized Clinical Trials Through Systemic Review


Abstract
Objective: Coronary artery disease (CAD) is characterized by remodeling and thinning of the coronary arteries and is the major source of morbidity and mortality around the globe. Coronary artery bypass grafting (CABG) is the standard approach for the symptomatic relief and management of CAD in critical condition. Post-GABG patients has low quality of life and have long term complicated psychological outcomes. The present study aims to demonstrate the outcome of physical activity (PA) intervention on the quality of life of post GABG patients. Methods: 120 post-CABG patients from Two randomized controlled trials meet the inclusion criteria and they were studied systemically. Endpoint analysis in the present study included mental and physical components associated with the quality of life. Various statistical tools were adopted for data management, and 95% confidence interval and mean difference were used for analysis. Results: Mild-moderate PA, including physiotherapy intervention or exercise for 4-24 weeks significantly enhance the scores of QoL in post-CABG patients at the end of follow up period in intervention group (36.41 ±5.12) than the control group (25.39 ±6.22). In contrast to control group, scores of both mental and physical components such as physical function, psychological role, bodily pain, general health, social function, mental health and vitality were significantly increase in the post-CABG individuals of intervention group. Conclusion: In summary, these finding concludes that mild-moderate PA can enhance the quality of life in post-GABG patients, nevertheless, future studies will be required with large population before recommending PA in rehabilitation programs of post-CABG patients.

Keywords
Physical activity, Life quality, Post-CABG patients, Clinical Trials, Systemic review

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