Volume 29, Issue 4, 2020
DOI: 10.24205/03276716.2020.885
Predictive Value of Uterine Artery Blood Flow Value for Preeclampsia
Abstract
Objective: To investigate the predictive value of uterine artery blood flow value for preeclampsia.
Methods: A total of 70 pregnant women with preeclampsia (observation group) and another 70 healthy pregnant women (control group) who were admitted to our hospital from January 2016 to March 2019 were enrolled. The uterine artery hemodynamic parameters of the pregnant women were detected by color Doppler ultrasonography, the uterine artery blood flow value was calculated according to the color Doppler flow spectrum, and they were compared between observation group and control group. Besides, the uterine artery hemodynamic parameters and uterine artery blood flow value were compared among pregnant women with different degrees of preeclampsia, and the associations of uterine artery hemodynamic parameters and uterine artery blood flow value with the severity of preeclampsia were analyzed. In addition, the pregnant women were followed up and pregnancy outcome was compared among pregnant women with different uterine artery blood flow values.
Results: The uterine artery pulsatility index, resistance index, peak systolic to end diastolic velocity ratio (S/D value) and uterine artery blood flow value in observation group were higher than those in control group (P<0.05). The peak systolic velocity and the minimum diastolic velocity of uterine artery in observation group were lower than those in control group (P<0.05). The uterine artery pulsatility index, resistance index, S/D value and uterine artery blood flow value in severe preeclampsia group were higher than those in mild and moderate preeclampsia group (P<0.05). The peak systolic velocity and minimum diastolic velocity of uterine artery in severe preeclampsia group were lower than those in mild and moderate preeclampsia group (P<0.05). The results of correlation analysis revealed that the pulsatility index, resistance index, S/D value and uterine artery blood flow value were positively correlated with the severity of preeclampsia, while the peak systolic velocity and minimum diastolic velocity were negatively correlated with the severity of preeclampsia. In addition, there were statistically significant differences in the gestational age, neonatal weight and neonatal Apgar score among pregnant women with different uterine arterial blood flow values (P<0.05). With the increase of uterine arterial blood flow value, the gestational age, neonatal weight and neonatal Apgar score decreased.
Conclusion: Uterine artery blood flow value and uterine artery hemodynamic parameters are closely associated with the occurrence and development of preeclampsia, and they are valuable for predicting the pregnancy outcome in the case of preeclampsia.
Keywords
preeclampsia; color Doppler ultrasonography; uterine artery blood flow value; hemodynamics