Volume 29, Issue 3
DOI: 10.24205/03276716.2020.934
Study on The Pregnancy Outcome and Serum Biochemical Indexes of Cryo Embryo Transfer by Pelvic Floor Biomimetic Electrical Stimulation in Patients with Thin Endometrium
Abstract
To observe the pregnancy outcome of cryo embryo transfer thin endometrium treated by pelvic floor biomimetic electrical stimulation. Methods: six patients with thin endometrium were randomly divided into two groups, 30 in each group. The patients in both groups were given artificial cycles (taking estradiol valerate tablets (bujiale, Bayer Pharmaceutical Co., Ltd.) 3 mg in the morning and 3 mg in the evening from the third day of menstruation, adding luteal support after 12 days of continuous use). After being purified, the observation group was massaged with pelvic floor muscles every day for 15 minutes at a frequency of 50 Hz, and the acupoints were selected as perineum the endometrial thickness, type, blood flow and clinical pregnancy rate of progesterone were compared between the two groups.
Results: after the treatment of pelvic floor bionic electrical stimulation, the blood flow of type â… and type â…¡ â…¢ in the observation group was significantly decreased compared with that in the control group (P < 0.05); after the treatment of pelvic floor bionic electrical stimulation, the thickness of the endometrium in the observation group was significantly higher than that in the control group (P < 0.05); after the treatment of pelvic floor bionic electrical stimulation, the number of type a endometrium in the progesterone group was higher than that in the control group, but the difference was not statistically significant (P > 0.05); the clinical pregnancy rate in the observation group was significantly higher than that in the control group, and the difference was statistically significant (P < 0.05). After treatment, serum biochemical indexes of patients showed significant changes. Thromboxane A2/Prostacyclin (TXA2/PGI2) and Inhibin B (INHB) in observation group were higher than in control, while serum anti thyroid peroxidase antibody (TPOAb) in observation group was lower than in control group.
Conclusion: the combination of estrogen and progesterone combined with pelvic floor massage can improve the endometrial thickness and blood flow of thin endometrial patients undergoing Fe 'cycle, and improve the pregnancy rate.
Keywords
pelvic floor massage; frozen thawed embryo transfer; pregnancy outcome; thin endometrium