Volume 29, Issue 3
DOI: 10.24205/03276716.2020.747
Clinical Study on Serum Biochemical Factors and Vascular Crisis of Reconstruction of Oral and Maxillofacial Defects with Free Skin Flap
Abstract
Objective: To investigate the relationship between serum biochemical factors and free skin flap of oral and maxillofacial defects in the repair of vascular crisis.
Methods: 105 cases received oral and maxillofacial free skin flap transplantation from January 2015 to June 2017 were selected, including 9 cases of vascular crisis and 96 cases of skin flap without crisis. Based on the results of retrospective analysis, the corresponding biochemical factors were divided into crisis group and normal group. Fibrinogen, 2h postprandial glycemia, albumin, D-2 polymer and fasting plasma glucose were compared and analyzed in two groups.
Results: The incidence of skin flap crisis in patients with high fibrinogen, high fasting plasma glucose and 2h postprandial increase was higher than that in normal group, and the difference was statistically significant (P < 0.05). Based on the results of Logistic regression analysis, the high fibrinogen, high fasting glucose and 2h postprandial increase were all risk factors for vascular crisis (P < 0.05).
Conclusion: Preoperative high fibrinogen and high blood glucose may be associated with postoperative skin flap crisis.
Keywords
Free tissue flap, vascular crisis, biochemical factors.