Volume 29, Issue 5, 2020
DOI: 10.24205/03276716.2020.1125
Effect of group B streptococcus infection, vaginal flora disorder and premature rupture of membranes on maternal and infant outcomes in middle and late pregnancy
Abstract
Purpose: To investigate the effect of group B streptococcus infection, vaginal flora disorder and premature rupture of membranes on maternal and infant outcomes in middle and late pregnancy.
Methods: From May 2016 to February 2018, 145 pregnant women in middle and late pregnancy received group B streptococcus, vaginal flora and premature rupture of membranes respectively, and were divided into group B streptococcus positive detected group, group B streptococcus negative detected group, abnormal vaginal flora group, normal vaginal flora group, premature rupture of membranes group and unbroken foetal membranes group, and the effects on maternal and infant outcomes were analyzed.
Results: The incidence rates of premature birth, amniotic fluid pollution, postpartum hemorrhage, intrauterine infection, neonatal jaundice and neonatal pneumonia in group B streptococcus positive detected group and abnormal vaginal flora group were significantly higher in group B streptococcus negative detected group and normal vaginal flora group (P＜0.05), while there were no significant differences in the incidence of low birth weight (P＞0.05);The total incidence of adverse pregnancy outcomes was 94.00% and the total incidence of adverse neonatal outcomes was 64.00% in group B streptococcus positive detected group, which were significantly higher than 27.37% and 14.74% in group B streptococcus negative detected group (P＜0.05); the total incidence of adverse pregnancy outcomes was 95.34% and the total incidence of adverse neonatal outcomes was 67.44% in abnormal vaginal flora group, which were significantly higher than that in normal vaginal flora group (31.37% and 16.67%, respectively, P <0.05);The incidence rates of premature birth, amniotic fluid pollution, postpartum hemorrhage, low birth weight, neonatal jaundice and neonatal pneumonia in premature rupture of membranes group were significantly higher than that in unbroken foetal membranes group (P <0.05); the total incidence of adverse pregnancy outcomes (94.29%) and the total incidence of adverse neonatal outcomes (71.43%) were significantly higher than those in the unbroken foetal membranes group (36.36% and 19.09%, respectively, P < 0.05).
Conclusion: Group B streptococcus infection, vaginal flora disorder and premature rupture of membranes of pregnant women in middle and late pregnancy can increase the incidence of premature birth, amniotic fluid pollution, postpartum hemorrhage, neonatal jaundice, neonatal pneumonia and other adverse maternal and infant outcomes. Treatment should be taken as early as possible to ensure maternal and infant safety.
Keywords
Middle and late pregnancy; Group B streptococcus; Vaginal flora; Premature rupture of membranes; Maternal and infant outcomes