Volume 30, Issue 2, 2021
DOI: 10.24205/03276716.2020.4085
A Comparison Between Radiotherapy on Breast Tissue and The Complications Associated with Modified Radical Operation Procedures
Abstract
Breast cancer is a female malignant tumor. With improved diagnosis rate, surgery is the preferred alternative. We aim to compare the complications of breast-conserving surgery plus radiotherapy with the complications of modified radical mastectomy in 186 patients with stage I breast cancer. 186 patients were equally assigned into two groups, 98 patients with breast-conserving surgery received 5-6 periods of radical radiation therapy after six periods of CMF (cyclophosphamidu, methotrexate, and fluorouracil) and 86 patients received chemoradiotherapy after modified radical mastectomy. Our results revealed that the complications of breast-conserving surgery were significantly less than that of the modified radical mastectomy, such as upper limb lymphedema, intercostobrachial nerve syndrome, shoulder movement limitation, axillary vein and thrombus injury. However, there were no statistical differences between the overall survival rate and the local recurrence rate of both. In conclusion, breast conserving surgery combined with axillary radiotherapy displays fewer complications compared to modified radical mastectomy with axillary lymph node dissection (ALND).
Keywords
breast cancer, radiotherapy, modified radical operation, efficacy