Volume 29, Issue 3
DOI: 10.24205/03276716.2020.947
Comparison of Diagnostic Value for Glioblastoma Between Conventional and Multi-Slice Spiral Computed Tomographies and Analysis of Factors Affecting Patients' Prognosis
Abstract
Purpose: To explore the correlation of the computer tomography (CT) examination results of glioblastoma (GBM) patients with their histopathology.
Methods: A retrospective analysis was performed on 40 patients with suspected GBM, treated in our hospital from November 2011 to May 2015. Among them, there were 30 cases diagnosed with positive GBM by pathology. These 40 patients were scanned via conventional and multi-slice spiral CTs, respectively, and the scanning results were compared with those of the histopathology to analyze the efficacy of two kinds of CTs in the diagnosis of GBM. Logistic univariate and multivariate analyses were used in the analysis of factors affecting the prognosis of GBM.
Results: In the diagnosis of GBM, the sensitivity, specificity and consistency rate of conventional CT were lower than those of multi-slice spiral CT (p<0.05). According to the results of Logistic univariate and multivariate regression analyses, the independent risk factors for the poor prognosis of GBM included the position where GBM occurred, its degree of resection, cystic degeneration, intracranial infection, concurrent radiotherapy and chemotherapy.
Conclusions: The application of multi-slice spiral CT in GBM excels the conventional CT scanning and screening in the diagnostic efficacy. When conventional CT is not accurate enough to determine GBM lesions, multi-slice spiral CT is able to provide more refined imaging. The independent risk factors for the poor prognosis of GBM were the position where GBM occurs, its degree of resection, cystic degeneration, intracranial infection, concurrent radiotherapy and chemotherapy.
Keywords
glioblastoma, conventional CT, diagnostic value of multi-slice spiral CT, prognosis