Volume 29, Issue 3
DOI: 10.24205/03276716.2020.750
Clinical characteristics and mortality-related risk factors of septic shock in Emergency Intensive Care Unit
Abstract
Objective: To discuss the clinical characteristics and mortality-related risk factors of septic shock in Emergency Intensive Care Unit (EICU).
Method: The clinical data of 201 patients with septic shock hospitalized in the EICU of our hospital from June 2017 to June 2019 were studied retrospectively. Combined with the summery of the clinical characteristics, univariate analysis and multivariate stepwise Logistic regression analysis were applied to identify risk factors in mortality of septic shock.
Result: In the 201 cases of septic shock patients, there were 121 males (60.2%) and 80 females (39.8%), with the mean age of 57.15 ± 16.54 years old. The mean number of dysfunctional organ was 3.29 ± 1.60. The abdomen was the most common site of infection (45.3%), and cardiovascular disease was the most common underlying one (41.7%). The overall mortality of septic shock was 53.2% (107/201). The mortality of male was higher than that of female (60.4% vs. 42.9%, P<0.05). The multivariate logistic regression analysis showed that the number of dysfunctional organ and intravenous use of sodium bicarbonate were the independent risk factors associated with death. Hemopurification and length of stay were the protective factors.
Conclusion: The mortality of septic shock is extremely high. It may play a key role in decreasing mortality of septic shock by use of early and active rescue, the use of hemopurification and other rescue measures to prevent organ function impairment.
Keywords
septic shock, EICU, clinical characteristic, risk factor.