Volume 29, Issue 3
DOI: 10.24205/03276716.2020.751
Relationship between obesity and NT-proBNP and the effect on prognosis of acute myocardial infarction
Abstract
Objective: To explore relationship between N-terminal pro-B-type natriuretic peptide (NT-proBNP) and obesity, and effect of them on acute myocardial infarction prognosis in patients
Methods: Sixty cases patients who were diagnosed with acute myocardial infarction, were enrolled from December 2015 to December 2017 in the author's hospital. Thirty of these non-obese patients were divided to control group, and the remaining 30 patients with obesity were assigned to the observation group. NT-proBNP was measured in both groups to observe the prognosis, and explore relationship between obesity, NT-proBNP and prognosis of acute myocardial infarction.
Results: Level of NT-proBNP in the observation group was significantly higher (2234 ± 1457 pg/ml) than that in control ones (1126 ± 826 pg/ml), and adverse cardiac events incidence in observation ones was 13.3% (4/30), which was significantly lower than the incidence of 40% (12/30) in the control group (P < 0.05).
Conclusion: NT-proBNP is higher in obese patients, and could be applied to judge prognosis of patients with acute myocardial infarction in obese populations
Keywords
Obesity, NT-proBNP, Interrelation, Acute myocardial infarction, Prognosis, Effect.